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Heartworm tests use a blood sample to detect either a specific antigen released by mature female heartworms or the offspring (microfilariae) of these worms.

It generally takes 6 months from the time the pet is infected with heartworm larvae by a mosquito bite until female worms can be detected. The administration of heartworm preventives to dogs with mature female worms can delay their detection for up to 9 months after infection.

This means that a dog may test “negative” for heartworms, even though it has adult worms in the heart and blood vessels of the lungs.

What is the basis for the Window of Infection time frame?